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During that period, the number of HCV-related cirrhosis cases is estimated to increase by 31% and HCC by approximately 50%[6] with an additive effect due to the occurrence of the metabolic syndrome[8,9]
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In these diseases, α-syn misfolds and aggregates in a prion-like amyloidogenic cascade culminating, in PD, in the formation of higher-order aggregates termed Lewy bodies (LBs) and Lewy neurites
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