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Compared to the parent compound 1, these inhibitors exhibit a 28-fold increase in SHMT2 inhibition, a 21-fold increase in SHMT1 inhibition, and an 11-fold increase in glycinamide ribonucleotide formyltransferase (GARFTase) inhibition [166]
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doi: 10.1111/bph.13139 171 CraddockTJAMichaloviczLTKellyKARiceMAMillerDBKlimasNGet al
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